i have an r75/6, had a cb550 ( and a bunch o' others over the years). have had my r75/6 since 1980, and never, ever not started nor left me stranded. i'd stay away from the 4 speeds btw.
engine/trans -- power rating is low, revs a little slowly, and shifting is wonky. (ka-chunk!). some day you might get used to the bike rocking a little as you blip the throttle due to the engine layout. as with any non-faired bike, windblast is the only limiting factor for cruising speed. it'll travel all day at 70mph if you'd like but it's tiring. top on mine is 110 indicated, in prone position (think rollie free). periodic maint is stupid easy.
handling/brakes -- with modern tires, turn-in and mid-corner stability is very nice. i'd recommend progressive springs and experimenting w/different fork oil weight for damping. regarding brakes, they were adequate for the time. with a new brake cable and ebc pads, i can dive the front end pretty easily, but takes 3- 4 fingers.
ergos -- even with my "S" Magura bars, the ride position is upright, comforable. the seat is perfect, not too hard nor too plush. they got it right. much is made of the blinker switch position, it's nothing.
expect the same power characteristics if you move around to the r90, r100 etc. i've heard that in much later years bmw shifting has improved so it's less clunky. bottom line is that any early "R" will accelerate somewhat slowly, shift a little klunkily, brake adequately and probably outlast you.