One thing to remember Alex, when you start to bore these bikes out, you generate a lot of heat.
The advantage of Mikes cylinder block is it was designed as a 1000 and won't develope the heat that a cast iron liner bored to the limit will. You will also have noticed the problems of boring the stock block beyond it's limits in the thread that is running at the head of this forum at the moment.
Mikes block is also lighter with being all alloy (no sleeves) so that's another big pluss.
I think the numbers you are talking about are acheivable but you would have to build a lot of reliability measures into the motor for endurance racing.
I know the people that built and tested the 69 Bol-d-Or winner and they will tell you, that was almost a stock motor. You saw what happend at Daytona the Year after when they bumped up the power from 67 to 96 at the crank, they strugled to last 200 miles.
An 836 with a 125-70/75 cam will push those figures with complete reliability and the figure is at the wheel not the crank but it will not turn the speed of the factory bikes because they made their power much higher up the rev range.
I think the big block with 12 to 1 pistons and a 125-70 cam would get you where you want to be and there are a couple of other options that I know nothing about. First you have Big Jays stroker crank (not sure what your capacity limit is) and Megacycle do a 125-X12 cam which should bang some more out but I don't know any figures for this cam.
A set of Carrillos and plenty of oil coolers and you could be in business.
Sam.