GB500, XR500, and SR500 (Yamaha) are all thumpers (singles).
AFIAK, if you're looking for a parallel twin, then the largest classic looking air-cooled one from Honda is the CB500T. Anything larger from Honda is going to be a V-twin, four cylinder, or thumper (XT/XR 600 & 650).
You can get larger from Yamaha in the XS650 (TX750 -- don't remember if that was a twin or triple), or from Kawasaki, as they had a KZ750 that was a twin.
I dunno if Suzuki did any big parallel twins or not.
Avoid the Yamaha TX500 DOHC motor, it had a lot of design problems.