If you screwed it down it would force the valves open which is okay but you could not torque the cover down properly.
The cover would leak worse case. You need to loosen the adjusters so the cover fits flat with no restriction and torque the cover on according to the proper sequence. Also tighten in increments just like cylinder bolts. This ensures even pressure throughout the cover and prevents warping.
You need to re-adjust the valves as the final procedure. Leave the spark plugs out. It makes it easier to turn the engine while moving the crank to the proper timing marks for the different cylinders.