The shop manual does NOT state that the engine should be running. I both read it, I printed it out to a fellow cb750 rider and discussed it with a honda mechanics since 1967. Static and 15 ATDC is the way that's stated in the manual, at least the manual for my bike. The honda mechanics first thougt it could be running but then quickly changed to that this was the later on cb900 and perhaps the DOHC 750(at least what he could recall, he's starting to get old these days).
I just wanted to be clear on that point.
If the manual you are referring to is for your K2, that's the point. The earlier manuals, pre K7, had the static method. The later ones had the running method.
I was in a cam chain thread a few years ago where a copy of the pages of the K7/K8 manual was posted and sure enough, it very clearly stated to adjust with the engine running. And it was referring to the CB750, no mistake.
Nothing had changed in the design of the parts, so I still maintain that the static method is better.
But people stating they read the running method in a CB750SOHC manual are not crazy, they read it. AS have I.
PS: And in that thread several people stated they did it while running and got an acceptable result.