Yes. I once helped out a guy with a 75 cb750 with all stock jetting.
He had totally open pipes, K&N filters, you would think he would need to do some rejetting and at least rejet, but the bike seemed to run ok, except the idle would runaway at times and not come back down.
Fiddling with the air screws seemed to have little affect.
He did notice that when he pushed down on the linkage for the carbs, the idle would come back down, he thought they weren't closing all the way. I however, noticed that if you pushed down on the carbs anywhere, not the linkage, if you just even grabbed a float bowl drain and pulled it down, the same thing would happen.
He had air leaks on his manifolds and pushing on the entire assembly would seal it up. I think those air leaks were making him run richer to the point where the bike was ridable.
I don't know if he ever got new boots though.