So you would be confident running it on a cb550
Around the block? Sure. It won't hurt the bike. Your wallet? ...maybe.
An LiFePO4 battery will be damaged if you let its voltage fall below 10V or allow the voltage to rise above 14.8V. The stock electromechanical regulator it rather sloppy in it's battery maintenance chores and relies on the "forgiveness" of the lead acid battery. If the Vreg is not tweaked/tuned correctly it can allow the battery voltage to go above battery manufacturer's guidelines. (so you can kiss warranty goodbye.) As far as I know, there is no automotive voltage regulator commercially available that provides specific protection for an LiFePO4 battery.
Recall that the Cb550 alternator doesn't charge at idle, which drains the battery. Idle or run low RPM for a long enough duration, the battery can/will deplete. You can't tell during operation that this is occurring if you don't have a voltmeter for the operator to constantly monitor. Needless to say, that the first time you leave the lights or ignition on when parked, the battery will be damaged or at least lose its full capacity.
So yes, it can "work" on the Cb550, but the extra operator workload and equipment required to ensure the LiFePO4 survival was unattractive to me.
But, if you are willing to throw the dice on your wallet, go for it. The battery or bike won't blow up because of the battery. But, do get a balance charger to have the internal cells equalized periodically, if you wish to avoid early replacement.
I just didn't want to tweak my functionally working, stock, original, regulators to compensate for an LiFePO4 battery needs, and didn't particularly want to add a voltmeter, either. (Though I did acquire one.)
I just recently bought AGM batteries for my bikes. Still have to install them. But, that technology dovetails with the same needs as standard lead acid.
Cheers,