I've never used a Weber, but know they are in high regard. These use a butterfly valve for the throttle, right?
How well do the butterfly pivot shafts hold up to the strong induction pulses? Is there a replaceable bushing there? Just curious.
I can see how they might help power at red line operation. But, it would seem like operation below mid range and the low air velocities, would make the engine less responsive on the street.
Putting big carb throats on small engine is a common mistake for a happy street machine, resulting in poor low speed atomization. Works well for drag racing, high speed runs, though.