Fouled spark plugs are just a symptom of incomplete combustion.
A variety of issues can cause incomplete combustion.......
1) Weak spark or spark at the wrong time - or maybe bad plugs
2) Valves too tight (never totally close) or leaking
3) Poor compression - bad valves, bad rings, maybe cam timing out of whack
4) Too much fuel or too little air - carb float, jets, dirty carb, etc.
5) Restricted air filters or exhaust - I've seen both, usually due to critters looking for a home, or mud (on dirt bikes in particular.
Remove them, shake like crazy, blow air into them, run coat hangers through them - whatever works to assure they're not plugged.
But there are other possibilities as well.
I'd be very careful about messing with your jets and slide needle. In good trim the bike should run well with stock jets/center needle clip, assuming you have stock mufflers and air cleaners.
Fooling with the tapered needle can cause the bike to run better at some rpm, worse at other rpms. You can end up really creating a mess for yourself.
This is one of the few bikes I don't have the manual for - but I'm fairly sure that 110 psi is not an acceptable reading - as I said before this assumes the readings are accurate. Again, the CB450 sports a similar compression ratio, but Honda expects 180 psi compression readings - in fact they recommend top end work at the "red flag" level of 162 psi......it's in the Manual....and they're not fooling based on my experience. They are Hondas, they will TRY to run no matter how bad they are - I've seen them try to start and run with only 110 psi. But the difference between a CB450 with 180 psi and one with 140 psi is startling.
Warm engine if possible, wide open throttle, NO CHOKE.
Take several readings, then squirt a bit of motor oil into the cylinder.
Then take more compression readings - if it increases dramatically, that's usually a sign of bad rings.
I keep harping on it because it's the most basic kind of diagnostic info.
When you go to the doctor, first thing they do is take your pulse and blood pressure, doesn't matter you're there because your knee hurts.
If your blood pressure is 180/140, the doctor won't care about your sore knee, you have other more pressing concerns.