Why did the factory off set them? surely not just for fun.
Some HD's have off set wheels to compensate for the bulky and weighty primary drive. No doubt some other bikes do too.
In a way it makes sense, if you consider a wheelbarrow that has all the load on one side then off setting the wheel would help.
Having said that though, these Honda's do not look obviously lop sided so the question remains, "Why did they do it?"