Yep, you can buy a new tyre every time you run over a nail, but that can get real expensive real fast, especially if you live near a major construction area like I do.
As previously mentioned, I bought a BMW K1100LT from a friend that had a plugged front tyre that was done at the BMW dealer, and it lasted for the life of the tyre.
How many people would buy a used bike and inspect the tyres thoroughly to the point where they find a near invisible plug before they rode it?
I usually replace the tyres on a bike when I buy it (the Michelins on my VFR750 were close to 20 years old) because new tyres can really change the dynamics of a bike, but for most folks, unless you told them, they wouldn't even know if a tyre was plugged, if it was done right.