Nicolai- as others have suggested the simple answer to your simple question is : IT DEPENDS.
It depends on a lot of things. It's like asking "shouldn't this pizza taste better?" How many variables are there in that!!? Even more here. What is your gearing? Is your clutch slipping? What are your carb settings and hard parts? Are the float levels perfectly correctly set? Is your petcock flowing enough? At full tilt with wfo throttle it needs to gulp gas, not sip. And the pods are not as good as the OEM air box at high speed because you have a lot of high pressure, fast moving air ripping past the outer two carbs (1 and 4), which creates a low pressure area in the middle for carbs 2/3.
So your synch at idle is now basically meaningless and your carbs are struggling to function in the various kinds of dirty air. I worked on a bike that would barely pull 80 if I rode it with my knees splayed out, but got to 100 or so if I squeezed my legs in just next to the outer carbs. Don't believe me that airflow at high speeds (anything over 60, basically) is a real thing? Stick your head out a car window at 100 mph, face the wind directly and try to yell ALACRITY IS AN IDIOT."
Now, after the (likely) coughing fit subsides, turn your head 90 degrees to the oncoming blast and repeat. When the tingling sensation from your hyper-vibrating lips subsides, face the back of the car with the wind hitting the back of your head and try again. Multi-cylinder bikes need matching everything: compression, fueling, air, spark, timing, etc in all the combustion chambers. Pretty much everything done in a "tuneup" is there to support this need and address any aberrations.