I had a friend with a van that burnt with 3 bikes in it... same thing, all aluminum gone. Just fallen frames with the cranks and gears in piles under where the engines had been.
Anyway... the 400/466: should be fun! I would suggest a mild cam, Yoshi street or megacycle 131-00, or whatever webcam has that's similar.
Boring the carbs opens up the top end, but the stock rods are getting rather stressed above 10500 or so. You could take a second mortgage and put in Carillos of course...
Stock airbox is good, a free flowing filter might improve breathing, pods are a right bugger to tune but can work well if you take the time to tweak the carbs.
A Yoshi or OMT replica exhaust - and I'm sure there are others - will improve upper rpm power, both are rather loud in anger but tolerable when putting around the neighborhood. Many love the stock exhaust and it's not really bad.
Suspension should be upgraded. Good shocks for sure. The forks are thin and flexible... but good springs, new seals, and some fiddling with fork oil viscosity is worthwhile. Upgrading is an option: Honda 450 triples are the right offset and their forks are much better than the 400F... but are getting rare. I have seen sportbike triples and forks on a 400, it looks like too much work for me and I don't know what the geometry does to handling.
Tires - the stock rims (1.65/1.85-18) are too narrow for tires much wider than stock, but a 3.5 (90 metric) is ok up front and a 4.0 (100) works on the rear. You need wider rims to go bigger without rolling the tire profile under. Much more than a 90 may not fit into the forks, maybe a 100 will?
The front brake is sufficient but not excellent. Not much is possible because of the very limited space for a caliper between the fork leg and the spokes. Good pads, SS lines, and a drilled disc are pretty much all that's usually done. The front brake (and all Honda SS discs of that era) is somewhat scary in rain but drilling it gets rid of the 1/2 second of "CRAP! NO BRAKES!" with a cold wet rotor.