Some people do that kind of stuff often, but you need a lot of equipment and knowledge to pull it off, and no fear.
I know a guy that does it often, stuff like v twin turned into a single, blowers, turbos, oil pump build to pump more out of lower end on turbo motors , bigger seats, change valve angles, radically weld and reposition ports, cut up cams and reweld them,undercut gears, frame raking and building. He has a dyno to test, did a few bikes fir Bonneville.
So he is my go to guy to ask questions..but a very busy guy.
I have a 72 750 head that I pulled the spigots out of, put bigger manley intakes in..was thinking, maybe I should raise the intake ports a bit and make new spigots.... Was thinking to run that by him
Here is one of his bikes. There is a disc brake inside the front hub.