Back when I had a Tiger 1050, there was a rumor - not sure how true, that the latest versions rolling off the line would null out the ECU if you tried to flash them with anything but factory diagnostic equipment. That meant you couldn't use TuneECU to tweak your bike. They did that to specifically enforce the regulations.
Again, I don't know if that was just rumor or true or only true in certain countries (like UK or Australia). If so - I would imagine that presumably Kawi, Honda, etc would do similar things.