*IF* all four cylinders are identical, and the valves are adjusted the same for each cylinder, and your bench sync is perfect for each carb, the vacuum should be equal.
However, the machine is designed and adjusted by humans who are incapable of making anything perfect. So, the vacuum sync compensates for imperfections in your specific example of the man made machine.
As mentioned, it makes the most difference at idle in run smoothness, minimizing transmission gear clack as the cylinders fire unevenly, as well as clutch basket noise and primary chain noise. Some examples of machines benefit more than others, due to mentioned variables. Some here claim to have perfect machines. You are welcome to believe them.
Finally, new motors with multi cylinders don’t wear evenly, making volumetric efficiency drift with run time. That’s why it is checked each tune up interval. A vacuum sync means you don’t need to take the carbs off to do a mechanical sync.
Philosophically, multi cylinder bikes need specific tools to make them run well. Screwdrivers, wenches, air compressors, and other specialized tools are needed to repair and maintain them. You either have these tools for the machines needs, or you pay a shop to do it for you that does have the tools. What vehicle that you buy today doesn’t need specialized tools? And why do you think a machine would never need those tools?
Yes, I do have vacuum sync gauges. Not needed for adjustment at every check. But sometimes they are, and I’m grateful not to do a bench sync to bring them all into smoothest idle as part of the routine tune up. I bought my set way back when money was tight. Not a daily tool. But, I still don’t regret the purchase.
Cheers,