Syncing carbs really only matters when they aren’t in sync now. To get the motor to run smoothly, each cylinder should get the same air/fuel charge from separate carbs feeding four separate cylinders that only have one thing in common, the crankshaft.
The 500/550 does not have a primary chain tensioner. If The cylinders don’t fire with even strength in sequence, the crank slows or speeds during that sequence, making the chain slack a then tighten. Also, the trans gears are always meshed, even when not engaged, cylinders fighting for crank revolution dominance make those gears alternate tooth face contact. I call this trans gear clack, which gets really loud during idle when the carbs are not vacuum synchronized, the trans in neutral, and the clutch engaged.
Cheers,