Understanding what these screws are may help in determining which way to rotate them. I am not familiar with the 650s, and all my SOHC4s have been early ones, which are equiped with air adjuster screws, not gas adjuster screws. I don't recall any bikes with gas screws, but I could be wrong. I do have experience with different types of Honda small engines(outboard, generator,lawnmower as well as single,twin and four cyl Honda M/Cs) and Honda uses both in these different motors. So...
Clockwise (in) closes the circuit (gas- leans the mix, air- richens the mix).
Counter Clockwise (out) opens the circuit (gas- richens the mix, air- leans the mix).
Have I totally confused the issue?