I just put an FZR rear wheel, its tire is a 150mm X18inches, and the first thing to rub is your brake arm, the second, is I have maybe a 1/4 inch between the chain and the tire, with the correct chain line, so I dunno how you'd run a much bigger rear than than with out messing the chain line up. Plus a 180mm rear tire is going to slow down your steering, and reduce your performance. 180mm tires are needed for the 110-140 horsepower motors to give them enough contact patch to allow them to accelerate with out melting down the smaller tires. last time I checked a fully decked out over bored CB motor might get you 80hp reliably, sorta seems like a little over kill. As per which rim might fit, I've done some rough measurements, and I might end up putting a YZF600, (not R6's) rim on the rear, it uses a 20mm axle, and from my best on bike measurements looks like it'll slide right in an F2's swingarm.