Well it's my understanding that Honda engineered the CX specifically for their Turbo application in the 80's.
That said, a CX 500 and a CX 650 were the target mills. Naturally aspirated the 500 was a dog. I suppose if you re-geared the trans you might have something.
I recently sold one that belonged to a shop regular. He wanted everything out of his little 500. First was exhaust made by me. Then came pods and a jetkit. Then came port and polish. Then came pistons out of I believe a couple of unknown 450 singles. Then the overbores were traded for 650 heads. Then it was some weird crank. The list goes on and on....
All in all we shaved about 100lbs off that sucker by cleaning up the frame and lower cases. Not to mention aluminum swingarm and ducati front suspension. (triple tree and all).
Still was a dog compared to one of my employees 550/4's with only an aftermarket exhaust. I don't question reliable. That thing ran in any configuration and in any type of weather. No leaks no noise nothing.
Maybe I suck at getting to the hidden power in engines.