Frame:
CB500-1002395
Engine:
CB500E-1002548
Is this standard? I'm pretty sure this was in a flood in 1975 and I'm just trying to research some of the history.
On Hondas, flood or no flood, engine numbers never match frame numbers. They should each be within certain ranges to confirm you have a K2 engine in a K2 frame for example. Yours are so close I can't imagine a problem.
And even if you had a K3 engine in a K2 frame, or such, no one counts off for that. To confirm flood damage, I think you would need to rely on visual inspection of the bike, looking closely for corrosion at wiring plug connections, rust in the headlight bucket (metal?) and the like.