The carbs for the bike are not set up properly if you can close off the pilot screws and the engine keeps running at idle. Turning them out too far usually effects low speed throttle response.
The screws on your carbs meter air from the air jet to be mixed with the fuel from the Slow jet, primarily for throttle settings of idle to 1/8 open.
The Carb slide and attached jet needle set the mixture for 1/8 to 3/4 throttle positions. And, the Main jet sets mixture for WOT position.
I caution you that carb adjustments should be made after all other tuneup items are addressed; Points, timing, spark plug cleaned/gapped, and correct heat range plug verified, tappets an cam chain adjusted, and air filter cleaned, renewed. Also any, leaks in the rubber couplers will make carb tuning "fun" (if you like repetative and futile tasks).
All the book value carb settings apply to machines as Honda sold them. Changes to exhaust or air filter may required a unique setting for your assembled components.
You might also want to learn to read your spark plugs, as the deposits can tell you whether your combustion mixtures are lean, rich or just right.
http://www.dansmc.com/Spark_Plugs/Spark_Plugs_catalog.htmlCheers,