If I remember correctly (from reading a couple things, though couldn't point you to said articles now), the first SOHC's were, in fact, jetted for sea level, Jetted for the roads near where they were built.
The k0 and k1 750's do run a tad rich, even a few hundred feet above sea level.
I can't say, and wouldn't know, if later jetting changes were made at the factory to be better for the higher altitudes that the bikes would be sold at, or for some other reason.
General rule of thumb, at least to start at, is about half (5) to three quarters (7.5) of a step down in size per 5000ft (for main jets. I'll talk about pilot jets a bit later), with erring on quater (2.5) to half (5) as the jet sizes get smaller (smaller than about 110's)
That is, if you have 98's, and are going up 5000 feet, 93's would be a good place to start.
However, you are running pods and an open(ish) exhaust. This makes things more difficult. There are also some rules of thumb for jetting for these. I posted one at some point on this forum, lemme see if I can find it...
Eh, something like this:
up 2.5 jet size for pod (K&N, Uni, generic) filter (single inside the air box)
up 2.5 jet size for drilling the airbox
up 2.5 jet size for both single K&N and drilled air box
up 5 on jet size for individual pod filters
up 5 on jet size for 4 into 1 exhaust
up 2.5 pilot jet size for every 3 (7.5) main jet size increase
Add up jet sizes and subtract 2.5
so, lets say individual pods (5) + a 4 into 1 (5) and subtract 2.5. That means a good place to start is 7.5 up
Again, depends on the bike, but this is just for starters.
But what this means is that pods and 4 into 1 may give a very close to correct jettings setting without changing your jets. Or if they arent right, they are very close (within 2.5, probably.. )
Now, I can't remember offhand, but I thought the cb350f stock main jets were 98's? (97.5, I guess..)
If so, that means 97.5 - 5 (for altitude) + 7.5 (pods and 4 into 1) = 100.00
As far as pilots go, it's been different for every damned bike I've worked on. Some bikes don't want any change on jet size, and don't need any air-screw adjustment. Some need minor enriching at the air-screw (and by minor, I mean 1/16 to 1/8th turn). Some may need just the next size up in pilot, but I've only seen this happen on bikes with larger displacement cylinders and much larger carbs.
Good luck.
