Well the '79cb650 has about 5 gallon tank, be glad you don't have a '80-82, they are like 4.2 gal or something just quoting outta my arse, but I think those #'s are close...
At 65mph on a flat run area, a average of 45 is "normal" from my experience for a '79cb650.
I have gotten as low as high 30's to mid 60's for MPG.
All depends on your throttle use and shifting habits.
On my last long trip(Provo,UT to Las Vegas, NV) I averaged about 40 mpg.
Keep an eye out for other drivers if you must ride at dawn or sunset.
I would suggest pulling over to watch them for an hour before riding again.... cage riders can't see well with the light in their eyes....
Just for "reassurance" I filled up every 150 miles when I could.
The longest I have gotten off of one tank(including using reserve), about 240 miles....before I chickened out and stopped for gas.
If you are worried about running outta gas, search out a 1 gallon gas can, and strap that baby on somewhere.
Be careful at sea level with those carbs, try not to run WOT for too long.
Those PD50 carbs are jetted lean to begin with, and at sea level, they will be even leaner.
l8r