The F2 has a higher red line than the K models. And High RPM is quite stressfull to valve train components. It is also why the cam profile is more "aggressive".
Many of the changes and part recommended are chicken and egg issues, and have much to do with engine longevity. For this engine, simply not using the extra 1000 RPM red line will almost certainly lead to longer life even with the stock parts.
How much longer? ?? There are other factors to consider as well.
If the guides are pre hone and are interference fit into the head casting bores. What keeps the guide I.D. from distorting during press fit? Further, the act of driving them into place works as a forge to distort he end being hammered. These install issues can be minimized with heating the head in an oven.
If the stock valves are stellite treated, are the stainless offerings done that way as well? Is the stainless as hard as the stellite?
The keeper wear is from both the spring pressure and the reciprocating mass direction change severity (RPM). Titanium is longer lasting, particularly for High RPM operation. But, then for high RPM operation you need stiffer springs to get the valve back into its seat. (Chicken/egg) If you reduce the valve spring pressure, expect to lose stock red line reliability/ power with the stock cam. IF you replace the cam with one less aggressive, do you also lose power at high RPM? Do you lower the red line as well as power?
How important is keeping red line to you? To my mind the importance of the F2 head it that it offers both power and red line operation. Will you be happy with changing those characteristics? If so, why not get a K7-K8 head? Even a used one will be cheaper than a rebuilt one and give you the same longevity and reliability the CB750 is known for, albeit with less peak power.
Those are my thoughts...
Cheers,