Not having done this, don't take it as gospel... (but I've read about it quite a bit, as this is a mod I'd like to do at some point). My understanding is that there shouldn't be any interference w/valves, but some people have has slight problems with clearance in the head. You should just search "650 cam swap" and you'll get a bunch of posts about it - check them out and you'll find plenty of info about fixes, etc.
Cheers,
G