Mastery, no. But, some knowledge, yes.
Bear in mind the 78 750F carb are of different design than the CB550F.
Given that, all I can say is that if you didn't take it apart, you didn't change the sync. Vibration and wear factors can change the relative slide positions amoungst carbs from when is was synched at the factory or service center.
They only way to check if they are still in sync is to check them with manometers. And, I do this at each tuneup interval (3k miles).
As an example, my 74 Cb550 Honda didn't change its own synch for 5 years of riding. I almost began to skip the check. But, then I found it needed adjustment, which was also stable for a couple years. I'm unable to predict now when they will go out of synch. But, if it doesn't idle smoothly after the other tune up items are addressed, the manometer check usually shows and adjustment is needed. Then it is all smooth again for a while.
Cheers,