With the upcoming Indy GP, there has been a lot of press about motorcycling here. A recent interview with an ABATE of Indiana official on a local redio station disclosed this:
93% of motorcycle fatalities (didn't specify Indiana only or US) occurred to riders who had not taken an MSF or similar training course.
So, if one takes this course and especially if one refreshes every other year or so, one will reduce the chance of being killed to similar with falling in bathtub, riding a bicycle in traffic, etc.
40% of fatal accidents involved the rider being under the influence (not necessarily over the limit) of alchohol.
There is a saying among fighter pilots, and astronauts, often with a reputation for drinking, that there should be an appropriate delay "bottle to throttle". Often 12 hours, at least 8 hours.
Another rule of thumb is "an hour per ounce". Wait an hour per shot, per beer, per small glass of wine, before riding.
This matches closely with the "bottle to throttle" as a night's drinking often involves 8 to 12 beers, shots, etc.
JMHO