Until the harmonica came along?!
What- you're like 600 years old?
Uh, o.k.
Some Wikipedia cut and paste for the ignorant:
The harmonica was developed in Europe in the early part of the 19th century.
The first recordings of harmonicas were made in the U.S. in the 1920s.
The harmonica's versatility brought it to the attention of classical music during the 1930s.
American Larry Adler was one of the first harmonica players to perform major works written for the instrument by the composers Ralph Vaughan Williams, Malcolm Arnold, Darius Milhaud and Arthur Benjamin.
In the 1950's, the harmonica then made its way with the blues and the black migrants to the north, mainly to Chicago but also to Detroit, St. Louis and New York.
Now you know!