Because of the overlap of the fuel delivery sources in our carbs, the most accurate way to tune is to start with the main jet, get it right, first, then move to needle clip position, then pilot jet, then mixture screw. Each with its own plug chop or chops to dial it in.
how are you testing for rich/lean? plug chop or seat of your pants 'feel' ?
if you are unsure of your main jet, concentrate on that first.