the cb rim has no bead lock on it so if the tire goes flat, it will probably get messy fast.
From a safety standpoint, no you should not do it.
You can seal up the spokes so the tire does hold air, it is just the ridge that is missing for locking the tire on.
I thought about this to and there is an insert for mx tires that allows them to be tubeless but it is not made for a street bike.
I also though about welding in a ridge but my suspicion is that it would discolor the rim and probably not work the best.