If you have carbs with accelerator pumps, you can set the pilot screws for "max lean" which would be the fastest or peak idle speed. The PD carbs can be set with a very sensitive tach. But, all the screws should be pretty close to equal setting among them.
Carbs that do not have accelerator pumps, and an air bleed pilot screw are not set with a tach. They are set best response to throttle twist.
These carbs must run rich at idle because when the throttle is suddenly opened the carb throat vacuum is vastly reduced, which make the jets stop or greatly reduce their fuel flow. This, at the same time more air is allowed to pass the carb's venturi. To get the engine to pick up, the idle setting has to be over rich so the engine will pick up. All the carbs (and cylinders) should behave the same, so the pilot screw setting should be the same for all carbs. Faults elsewhere should not be "covered up" with unequal pilot screw settings.
Anyway, for non-PD/non-accelerator pump carbs, the idle mix is set just lean enough so the that the plugs don't foul during idle, but the engine will pick up when the throttle is twisted to one half of total travel and the engine will still pick up with smooth power from idle speed in any gear, which is an over rich setting.
Usually, the carbs are set to factory position to achieve this. The installation of pods or other induction mods change the carb throat pressures and stock settings then rarely apply. You have to find new settings to accommodate the induction changes.
Also, if the needle jet isn't sized or adjusted properly it can leak a lot more fuel into the carb throat than it should at idle throttle position. After market needles that don't conform to stock profile can also mess up idle mixture, making the air screw adjustment, er, "difficult".
Cheers,