For normal riding, they are very nice and quiet. Change the oil when you are supposed to and you are good. No oil slinging around like a chain.
On any bike, the transmission steals some power. The drive shaft steals some more.
The way the shaft drive reacts under load is different than a chain. A chain driven bike will pull the bike down where a shaft drive will lift it. Let me give you a picture. Your at a light, you are holding the front brake, you have the clutch in and you are twisting the throttle. While not letting go of the front brake, you start to slide the clutch out - the back of the bike will lift up. I have not noticed a chain driven bike do this.
So, to the part that will get ya. Your canyon carving the bike, your in a turn leaned over perty good and you goose it too hard coming out of the corner. That lift can push the tire out from under the bike.
When it happened to be, about 4 times, it would kick the back tire out while in a curve and fall back enough to slide on the K1 baffle I had on it and slide for a bit. Then, as it would start to slow down while sliding, the front tires would touch the ground and grab, flip up and over onto the other side and smash itself on the ground. Each time the tank had to be fixed.
If you ride it that hard, just know that is possible or just don't ride that hard.
The bike attached was mine, it was only about 1 year old off the showroom floor. No rear disk, no tach and speedo, that black engine cover had bondo in the hole and painted, the rear turn signals came off the front and it is not Ruby Red (it was twice).