I recently went to pods, and another guy in my shop did the same last year so I borrowed his carbs and they ran real nice so I copied the settings.
He has a 500 bored out to 550 and MAC 4-1
I have a 550, 650 cam, with a 4-2.
Both bikes seem to like these settings.
Main 120
Needles full Up
Float 27mm
Hopefully it's a good start for you.