On the computer i just replaced the USB ports all slowly died, not too sure why but one by one they failed.Try plugging a USB stick or something else in the port and see if it is working, if it is I would delete all printer info on your computer and do a reinstall with new drivers, make sure you have the current service pack on your system...
Mick
thats what i'm thinking happened
thinking about taking it to the local geek and let them look at it