Would the pilot screws being cranked down tight keep it from starting. These things were cranked down to the point that I may have to tap one out.
The pilot screws block the entire pilot circuit from delivering fuel. If the acell pump is working and the throttle held open the engine will start and race, but dies at/near idle settings.
The pilot screw tips have a very shallow taper. And must only be gently seated. Forced seating damages the seat in the carb body and even the screw itself. At worst, the tip seizes (even breaks off) in the carb body rendering the pilot circuit worthless, (and the carb body as well). At best it simply distorts the adjuster screw seat, making predictable settings impossible.
Also, do I need to completely separate the carbs from the stay to give it a decent cleaning. I have #1 and 4 off, but don't want to take the throttle linkage apart if I don't have to.
No, they can be cleaned as a bank. All the bits that get fuel deposit residue are accessible with the carb bowls off.
The pilot jets are pressed in, and really can't be reliably, predictably cleaned while installed. But, if you are confident they aren't blocked/restricted, they don't need to be removed.
They can be grabbed and pulled straight out. I use a soft jawed parallel pliers for this. But, they can be hard to find. Regular pliers can be used if you use a leather pads on the jaws.
Carefully check the stand pipes in the carb bowls for cracks.
Cheers,