Currently machining adaptor etc. for my CB550 using a Brembo P08 setup-this is what I am dealing with here.
1- The swept area on the stock disc is "huge" (tall) and most, if not all dual piston calipers run around 40mm at the largest, where stock disc is minimum 45-47mm, so in a nutshell, you will have acres of unused disc if you combine dual piston caliper with the stock disc.
2- Caliper body clearance- I am running a custom 24mm offset carrier, and my caliper body is running as close to the spokes as possible (few millimeters)-you only have so much space to deal with, basically you will be looking for a caliper that does not exceed 25mm from pad to backside of caliper, and this is disc diameter dependent.
3- I am going to run a 300mm disc for the clearance, anything smaller, and the system won't fit (with my P08 caliper).
Anyway, I used to do this stuff for a living many years ago on racebikes, so I have quite a bit of experience in this department, let's see some pics-