That is a concern, but it isn't all that bad..,maybe. Pull your valve cover and remove the guides you have access to. If they are complete, then definitely pull the engine to look for other parts since the rest of that guide might still be in there. If it is obvious that only one guide is missing that exact piece, then you might be okay to run it. I would be concerned that a PO might have caused other issues though, so I'd look through the entire engine/trans.
Camelman