Cribbed this from the brakewarehouse.com Brembo FAQ page...some interesting food for thought. Especially the part about rotors cracking when the hole edges aren't radiused or chamfered properly. Yikes!
I’ve heard that cross-drilled rotors are prone to cracking. Are cross-drilled rotors prone to problems?
Some people prefer slotted rotors because of problems that came about when cross-drilled rotors first came to market. At that time, quite frequently, the holes were drilled too large, penetrating the cooling vanes and were not radiused or chamfered. The end result was that the rotor lost its structural integrity and tended to crack, so slotted rotors were developed. They do help dissipate the hot gasses, but not to the same degree as cross-drilled, usually lowering operating temperatures about 100 degrees. We always recommend cross-drilled unless you are particularly concerned with structural integrity. In some cases, only slotted rotors are available.