From what I understand, the motor is much less sensitive about the muffler than the airbox. There is a good chance it will work without rejetting.
I have a 78F motor in my project with rebuilt head, 4 to 1 Cyclex headers and 18" reverse cone muffler. I left the jetting the way it was, I may need to move the needle or such, but I will start with the stock jetting and see.