There is a school of thought that says increasing the bore size and thus the volume of air of the engine mechanicals, increases the volume of air sucked through the carbs. The increase in volume of air, lowers the pressure, relative to atmospheric, from one side of each jet or metering device in the carb, to the other side of it. The jets, therefore draw more fuel than they did with the lower cc sized engine. Unless you increase the bore size of the carbs, too, you may need to REDUCE the jet sizes.
Or...
There are also air metering jets in the carb that aren't commonly changed. One of these air jets is adjustable as your idle screws. Another, is fed from a small tube you will notice is in the intake side of the carb bore. This tube feeds air to the emulsion tubes located between the slide needle jet and the maiin needle jet. Somewhere along this inlet tube is an air jet. It is not one that is replaceable but is drilled during manufacture. Exact specifications for the K2 are hard to locate. The Honda shop manual lists a #120 air jet (pg.225) for the F model, which by the way has a 105 main jet. And a #150 (pg 257) for the K7K model, which has a #120 main jet. But, these are also very different carbs between these models.
Then there's the emulsion tubes that use the air from the air jets. The emulsion tube itself has holes drilled into it, and the sizes and placement along its length govern air premixed into the fuel before in enters the main venturi. I haven't found any documentation about these hole size specifications for the CB750. But, there were differences between the CB500 and CB550 emulsion tube hole sizes (.7 and .9 respectively) I assume to be attributable to the bore size increase. (same carb bodies) But, I admit I don't know this for sure.
At any rate, if your plugs are going sooty, you can certainly change the airscrew settings easy enough. If you turn them out too far, you'll probably notice a loss of throttle response from low rpm. You'll just have to turn them back in a little bit. If your plugs still get sooty after that, then slow jet, needle, and mains will probably need addressing. Or, you could experiment with air jet and emulsion tube hole sizes to get more air into the premix.
Sounds like fun, eh?