I'm sort of wondering this myself. I synced mine back in March and they are still running much smoother than before, but you can always get better
I sometimes worry about the adjuster nuts shifting tho, even tho they a double nuts. The way the throttle bar wishbones and adjuster nuts ride against each other... make me wonder.
On a related note: Tap your carbs. I bought a Motion Pro meter and after going thru the whole sync process twice last year I made an easy move in the off season. I bought a set of four 5mm vacuum fittings from Dennis Kirk and put them in my carbs where the vacuum port screws normally go. No more unscrewing those and screwing in the Motion Pro taps to do a sync. I just leave the fittings in all the time with rubber vacuum covers - just like any modern (well as modern as carbs can be these days) carb would have. It makes the whole process SO much easier. Just lift the tank, hook up the four lines from the manometer, do the sync and unhook. Makes it a 10 minute deal. Highly recommended, makes doign more frequent syncs seem much less daunting.
Lose the vacuum port screws, you won't miss them.