Do you have the stock screws in it? Reason I ask is I once used Keyster kits. Thought it wouldn't hurt to put in new kits. The replacement screws had holes in the bottoms. The stock did not. Couldn't keep plugs from seroiusly fouling around town. Put the old stock screws back in and no more problems. I need to mention I'm riding a 75 750F. Our carbs are different and I don't have a clue about yours.
I haven't changed the fuel screws, if thats what you're referring to, but maybe PO did. I don't see any holes in the screws. I think your carbs have air screws, mine directly control the amount of fuel in the idle mixture, so i don't think there should be any holes in them.