Those holes on the original manifold have a specific angle to them so the vacuum sync can be done. You can't just drill holes Willy-nilly and expect then to work. Also, they will need to be plugged with a screw for normal operation, so be sure you get one short enough so that it doesn't extend into the manifold and disrupt the airflow.
I'd get a real, proper manifold if I were you. Trying to drill these out and making them work sounds like a PITA to me.