You do NOT want silicone on that seal. It will contaminate the brake fluid. Not good.
The proper fluid is brake parts assembly lube (not commonly found anymore, you have to look for it). It is totally compatible with DOT3,4, 5.1. So, it is ok if it get on either side of the seal.
Brake fluid is often used for assembly, which is better than dry. However, there will be some on the pad side of the seal. Since brake fluid absorbs water, you can expect faster corrosion of caliper and piston. The assembly lube doesn't absorb water.
You'll note that water can easily get behind the brake pad and help corrode all the metal behind it. That is what the thin coating of silicone on all the exposed, unpainted metal bits is for; it sheds water away from the metal and it can't wash off, keeping the caliper healthy and operational.
Cheers,