it's ok to use harley parts, that's why the bikes were made... to make other bikes cool.
I'd say use the hub and get a shouldered aluminum rim and thinner gauge spokes from Buchanan.
The Harley spokes don't need to be that thick and heavy, it's overkill.
and the rim is super heavy too.
it has to be heavy cause it's Amurkun Steel VRROOM!
(Taiwan spokes and Italian rim)